After Star Camp wrapped, Cannon considered a solo career for Mandy, but decided instead to use her as the nucleus of a girl group; he also formulated a movie concept about three private school girls who meet in detention.
Cannon brought in Monica Anne Parales, who had auditioned for "The Giggle Club", but wound up working on the "Jam X Kids" project instead. Jasmine Villegas was the original third member of the group, but left early on to pursue a solo career, after which Jacque Pyles was chosen.
The School Gyrls made their television debut with Nick Cannon on the season finale of E! television series Party Monsters Cabo in January 2009. The group's first CD was released under the Island Def Jam imprint.
They opened for Korean-pop acts the Wonder Girls and 2PM at the House of Blues in West Hollywood, CA, on June 11, 2010.
The film, also called School Gyrls, written and directed by Cannon, premiered in February 2010. It centers around three teen girl and their lives in high school, and features cameos from Reverend Run, Vanessa Simmons, Justin Bieber , Kristinia DeBarge, Soulja Boy, Mathias Anderle, Diggy Simmons, and others. A Very School Gyrls Holla-Day premiered on Nickelodeon on December 4, 2010. A couple of weeks ahead of filming the holiday movie, Cannon announced he was adding two new girls to the group, (then) 15 year old Sade Austin, and 18 year old Lauren Chavez. They also recorded a new Christmas album, A Very School Gyrls Holla Day, released in December, and a single, "Going to the Mall".
Jacque Pyles and Mandy Rain left School Gyrls to pursue solo careers. Brittany Oaks and Natalie Aguero were added to the group.